STUDIES ON BIOLOGICALLY-ACTIVE HETEROCYCLES - PART IX - SYNTHESIS OF 3-[5-((2-CHLOROPHENYL)-1,3,4-OXA THIADIAZOLO)-2-YL]-1-ARYL/SUBSTITUTEDARYL THIOBARBITURIC ACIDS AS PROBABLE ANTIPARKINSONIAN AGENTS/

A series of new phenyl)-1,3,4-oxadiazolo}-2-yl]-1-aryl/substituted ary l thiobarbituric acids (6a-h), ophenyl)-1,3,4-thiadiazolo}-2-]-1-aryl/ substituted aryl thiobarbituric acids (7a-h), have been synthesized by reacting N-aryl/substituted aryl N-5-{(2-chlorophenyl)-1,3,4-oxa/thia diazol-2-yl} thioureas (4,5) with malonic acid in presence of acetyl c hloride. The structures of the newly synthesized compounds were elucid ated on the basis of their elemental analysis, physical and spectrosco pic data.