Since its introduction, fluorescein angiography has been widely used t
o investigate diseases of the ocular fundus. A case of fatal acute myo
cardial infarction after intravenous fluorescein angiography is presen
ted. This appears to be the first case documented by autopsy in which
the findings are compatible with myocardial infarction as the cause of
death. Although there are no known contraindications for fluorescein
angiography in patients with a history of cardiovascular disease, the
indications for this elective procedure should be carefully reviewed i
n such patients. Adequate emergency resuscitation equipment should be
available in the fluorescein angiography suite.