FLUVOXAMINE-INDUCED ERECTILE DYSFUNCTION RESPONDING TO SILDENAFIL

Sildenafil, a peripherally acting inhibitor of cyclic guanosine monoph osphate (cGMP), has been reported highly effective in treating erectil e dysfunction of various etiology. Erectile dysfunction is a common se xual side effect of various antidepressants. Various agents have been used in the treatment of antidepressant-induced erectile dysfunction; however, there are no reports on the use of sildenafil for this indica tion. This case report describes the successful use of sildenafil in f luvoxamine-induced erectile dysfunction. A possible mechanism of actio n of sildenafil in this type of erectile dysfunction is discussed.