PULMONARY-ARTERY INTIMAL SARCOMA - IMMUNOHISTOCHEMICAL FINDINGS

Pulmonary artery intimal sarcomas tend to be presented with symptoms o f pulmonary thromboembolism and grow regionally, with little capacity to metastasize. They probably originate from subendothelial cells, tha t become myofibroblasts. Knowledge of it is important to establish a p resurgery diagnosis, with the possibility of a total resection, the on ly useful treatment until now. We report a case of a pulmonary artery primary sarcoma, in a 73 year old woman, admitted with hemopthisis and pleuritic chest pain, who died ten days after. Autopsy revealed an in traluminal mass at the pulmonary artery trunk, without regional nor di stance involvement. Microscopic study showed a pleomorphic tumor with spindle and epithelioid cells, positive for actin, desmin and vimentin . All these data support the diagnosis of primary intimal sarcoma of t he pulmonary artery. We want to emphasize the myogenic differentiation of the tumor, uncommon in previously reported cases.