Few guidelines exist for the use of estrogen, particularly low-dose or
al contraceptives, during the perimenopausal years. Use of low-dose or
al contraceptive pills in women over 35 years of age provides protecti
on against unwanted pregnancy, maintains a stable hormonal environment
and decreases abnormal menstrual bleeding. Other noncontraceptive hea
lth benefits of oral contraceptives include a reduction in bone loss a
nd protection against iron deficiency anemia, dysmenorrhea, benign bre
ast disease, endometrial cancer and epithelial ovarian cancer. This ar
ticle discusses potential risks of oral contraceptive use in this age
group, as well as recommendations about when and how to change from co
ntraceptive therapy to postmenopausal hormone replacement therapy.