HARD END-POINTS FOR GH REPLACEMENT THERAPY - REPORT FROM AN INTERACTIVE DISCUSSION OF BONE STATUS AND CARDIOVASCULAR FUNCTION IN GH-DEFICIENT ADULTS

To stimulate debate and promote interaction between the audience and s peakers, an interactive session entitled ''Controversies in GH Replace ment Therapy'' was held at the 4th International hGH Symposium on GH D eficiency in Adults in September 1997 in Copenhagen, Denmark. The audi ence was asked to vote ''yes'' or ''no'' to a number of questions pert aining to the effects of growth hormone (GH) substitution in GH defici ency in adults on bone and cardiovascular function, respectively. This was followed by ''pro'' and ''con'' presentations on GH after which t he audience gave their second and final vote (answer) to the initial q uestions. The designated ''pro'' and ''con'' speakers were selected on the basis of their scientific contributions within the relevant field rather than their personal beliefs. This is a report of the interacti ve session. (C) 1998 Churchill Livingstone.