CHEMICAL STUDIES OF CHINESE LICORICE-ROOTS - II - 5 NEW FLAVONOID CONSTITUENTS FROM THE ROOTS OF GLYCYRRHIZA-ASPERA PALL. COLLECTED IN XINJIANG

Citation
I. Kitagawa et al., CHEMICAL STUDIES OF CHINESE LICORICE-ROOTS - II - 5 NEW FLAVONOID CONSTITUENTS FROM THE ROOTS OF GLYCYRRHIZA-ASPERA PALL. COLLECTED IN XINJIANG, Chemical and Pharmaceutical Bulletin, 46(10), 1998, pp. 1511-1517
Citations number
21
Categorie Soggetti
Chemistry Medicinal",Chemistry,"Pharmacology & Pharmacy
ISSN journal
00092363
Volume
46
Issue
10
Year of publication
1998
Pages
1511 - 1517
Database
ISI
SICI code
0009-2363(1998)46:10<1511:CSOCL->2.0.ZU;2-#
Abstract
From the air-dried roots of Glycyrrhiza aspera PALL. (Leguminosae) col lected in Xinjiang province, China (known as a kind of ''Shinkyo-Kanzo ''), five new flavonoid compounds named glucoisoliquiritin apioside (1 ) (a chalcone bisdesmosidic triglycoside), 7-O-apioglucosyl-7,4'-dihyd roxyflavone (5) (a flavone diglycoside), dehydroglyasperin C (7) (a pr enylated isoflav-3-ene derivative), asperopterocarpin (9) and 1-methox yphaseollidin (12) tan O-prenylpterocarpan and a C-prenylpterocarpan, respectively), were isolated together with four known saponins, one kn own flavonoid O-glycoside, two known flavonoid C-glycosides, and seven flavonoids, The structures of the new compounds have been elucidated on the basis of their chemical and physicochemical properties, Some pt erocarpan compounds showed moderate cytotoxic activity against KB and L1210 cells.