I. Kitagawa et al., CHEMICAL STUDIES OF CHINESE LICORICE-ROOTS - II - 5 NEW FLAVONOID CONSTITUENTS FROM THE ROOTS OF GLYCYRRHIZA-ASPERA PALL. COLLECTED IN XINJIANG, Chemical and Pharmaceutical Bulletin, 46(10), 1998, pp. 1511-1517
From the air-dried roots of Glycyrrhiza aspera PALL. (Leguminosae) col
lected in Xinjiang province, China (known as a kind of ''Shinkyo-Kanzo
''), five new flavonoid compounds named glucoisoliquiritin apioside (1
) (a chalcone bisdesmosidic triglycoside), 7-O-apioglucosyl-7,4'-dihyd
roxyflavone (5) (a flavone diglycoside), dehydroglyasperin C (7) (a pr
enylated isoflav-3-ene derivative), asperopterocarpin (9) and 1-methox
yphaseollidin (12) tan O-prenylpterocarpan and a C-prenylpterocarpan,
respectively), were isolated together with four known saponins, one kn
own flavonoid O-glycoside, two known flavonoid C-glycosides, and seven
flavonoids, The structures of the new compounds have been elucidated
on the basis of their chemical and physicochemical properties, Some pt
erocarpan compounds showed moderate cytotoxic activity against KB and
L1210 cells.