GASTRIC PERFORATION DUE TO MUCORMYCOSIS AFTER HEART-LUNG AND HEART-TRANSPLANTATION

Citation
C. Knoop et al., GASTRIC PERFORATION DUE TO MUCORMYCOSIS AFTER HEART-LUNG AND HEART-TRANSPLANTATION, Transplantation, 66(7), 1998, pp. 932-935
Citations number
10
Categorie Soggetti
Transplantation,Surgery,Immunology
Journal title
ISSN journal
00411337
Volume
66
Issue
7
Year of publication
1998
Pages
932 - 935
Database
ISI
SICI code
0041-1337(1998)66:7<932:GPDTMA>2.0.ZU;2-E
Abstract
Background. Gastrointestinal complications are a web-documented source of morbidity and mortality after heart and lung transplantation. Meth ods. We report on two patients who presented with gastric perforation caused by mucormycosis during the first 2 months after heart-lung and heart transplantation. Results. In the first patient, the clinical pre sentation was insidious and the diagnosis was made at an advanced stag e of the disease. Despite surgery and aggressive antifungal treatment, the patient died. In the second patient, the diagnosis was made promp tly, but despite antifungal treatment, he presented with gastric perfo ration within a week. Conclusions. These cases illustrate that fungal invasive disease may be a cause of early gastrointestinal perforation after solid organ transplantation.