EXACERBATION OF ATOPIC-DERMATITIS AFTER BACILLUS-CALMETTE-GUERIN VACCINATION

Authors
DALTON SJ HAENEY MR PATEL L DAVID TJ
Citation
Sj. Dalton et al., EXACERBATION OF ATOPIC-DERMATITIS AFTER BACILLUS-CALMETTE-GUERIN VACCINATION, Journal of the Royal Society of Medicine, 91(3), 1998, pp. 133-134
Citations number
6
Categorie Soggetti
Medicine, General & Internal
Journal title
Journal of the Royal Society of Medicine → ACNP
ISSN journal
01410768
Volume
91
Issue
3
Year of publication
1998
Pages
133 - 134
Database
ISI
SICI code
0141-0768(1998)91:3<133:EOAABV>2.0.ZU;2-K
Abstract
In two children with atopic dermatitis, routine vaccination with bacil lus Calmette-Guerin (BCG) was followed by severe exacerbation of skin disease. If the sequence is cause and effect, a possible mechanism is stimulation of a Th2 lymphocyte cytokine profile by the vaccine, with migration of activated lymphocytes to inflamed skin. In children with active atopic dermatitis, BCG vaccination is best deferred until remis sion.