Background Subfoveal choroidal neovascular membranes (CNV) are a cause
of significant visual impairment. Laser treatment of such lesions res
ults in visual loss, Surgical excision of CNV may allow stabilisation
or improvement of vision. A series of results of surgical excision are
presented. Methods The records for 43 eyes of 40 consecutive patients
undergoing surgical excision of CNV not associated with age-related m
acular degeneration (AMD) were reviewed retrospectively. Statistical a
nalyses of the relationship between pre-operative factors and past-ope
rative visual results were made. improvement or worsening of visual ac
uity was defined as a change of more than 2 lines of Snellen acuity. R
esults In 79.1% of patients visual acuity eras improved or unchanged f
ollowing surgery, and in 20.9% there was a reduction of Snellen acuity
. There was no statistically significant association between visual ou
tcome and age, gender, duration of visual symptoms, cause of CNV, pres
ence of subretinal haemorrhage, elevation of retina by subretinal flui
d, prior laser surgery, or the presence of pre-operative or intraopera
tive subretinal haemorrhage. There was a possible association between
the non-use of gas tamponade and an increased chance of reduced vision
, Visual loss was more Likely in those eyes with good preoperative vis
ual acuity. Recurrence of CNV was noted in 10 (23%) eyes; repeat surge
ry was not associated with a worse visual outcome. Conclusions Surgica
l excision of CNV not related to AMD is a promising technique. More me
aningful assessment of visual function in these patients will allow re
finement of case selection.