PRIMARY NON-FUNCTION AS THE RESULT OF UNSUSPECTED SEVERE STEATOSIS INLIVER-DONORS

Primary non-function is an serious complication after orthotopic liver transplantation. A relationship between the severity of fatty infiltr ation in the donor liver and immediate graft function has been describ ed. We present two cases of primary non-function, atributable to the p resence of severe steatosis in the donor liver. They were two recipien ts with a deteriorated clinical status before liver transplantation. I n both cases, liver fatty infiltration was not suspected because of th e macroscopic aspect of the donor liver at procurement. In time 0 biop sies, haematoxyllin-eosin stained sections evaluated the degree of sev erity of the fatty infiltration as moderate (30-60% of hepatocytes inv olved), while the Sudan stained sections revealed more degree of sever ity (more than 60%). We believe that in case of moderate steatosis in liver donor the graft may be considered when it is not associated to a nother known risk factors as poor medical status of recipient and retr ansplantation.