DIRECT LITHIATION OF METHYL ISOTHIOCYANATE - A NEW CONVENIENT SYNTHESIS OF MONO(TRIMETHYLSILYL)METHYL-ISOTHIOCYANATE, BIS(TRIMETHYLSILYL)METHYL-ISOTHIOCYANATE AND TRIS(TRIMETHYLSILYL)METHYL-ISOTHIOCYANATE

Authors
BRANDSMA L NEDOLYA NA VERKRUIJSSE HD TROFIMOV BA
Citation
L. Brandsma et al., DIRECT LITHIATION OF METHYL ISOTHIOCYANATE - A NEW CONVENIENT SYNTHESIS OF MONO(TRIMETHYLSILYL)METHYL-ISOTHIOCYANATE, BIS(TRIMETHYLSILYL)METHYL-ISOTHIOCYANATE AND TRIS(TRIMETHYLSILYL)METHYL-ISOTHIOCYANATE, Synthesis, (4), 1997, pp. 423
Citations number
21
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synthesis → ACNP
ISSN journal
00397881
Issue
4
Year of publication
1997
Database
ISI
SICI code
0039-7881(1997):4<423:DLOMI->2.0.ZU;2-L
Abstract
Methyl isothiocyanate/chlorotrimethylsilane mixtures in THF are readil y converted with lithium diisopropylamide at -95 degrees C to give tri methylsilylmethyl isothiocyanate, bis(trimethylsilyl)methyl isothiocya nate, and tris(trimethylsilyl)methyl isothiocyanate in 50-95% yields.