APPLICATION OF THE PD-CATALYZED HETEROARYLATION TO THE SYNTHESIS OF 5-(INDOL-2'-YL)PYRIDIN-2-ONE AND 5-(INDOL-2'-YL)PYRAN-2-ONE

Authors
DANIELI B LESMA G MARTINELLI M PASSARELLA D PERETTO I SILVANI A
Citation
B. Danieli et al., APPLICATION OF THE PD-CATALYZED HETEROARYLATION TO THE SYNTHESIS OF 5-(INDOL-2'-YL)PYRIDIN-2-ONE AND 5-(INDOL-2'-YL)PYRAN-2-ONE, Tetrahedron, 54(46), 1998, pp. 14081-14088
Citations number
41
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
54
Issue
46
Year of publication
1998
Pages
14081 - 14088
Database
ISI
SICI code
0040-4020(1998)54:46<14081:AOTPHT>2.0.ZU;2-7
Abstract
The synthesis of 5-(indol-2'-yl)pyridin-2-ones and 5-(indol-2'-yl)pyra n-2-one by Pd-catalyzed reactions is described. The best results are o btained using 2-indolylstannanes or 2-indolylzinc halides to be couple d with 5-bromopyridin-2-ones or 5-bromopyran-2-one in the presence of Pd(PPh3)(4) catalyst. Other Pd-catalyzed reactions are discussed. (C) 1998 Elsevier Science Ltd. All rights reserved.