CHARACTERIZATION OF ALLERGENS IN PLANT-DERIVED SPICES - APIACEAE SPICES, PEPPER (PIPERACEAE), AND PAPRIKA (BELL PEPPERS, SOLANACEAE)

Authors
EBNER C JENSENJAROLIM E LEITNER A BREITENEDER H
Citation
C. Ebner et al., CHARACTERIZATION OF ALLERGENS IN PLANT-DERIVED SPICES - APIACEAE SPICES, PEPPER (PIPERACEAE), AND PAPRIKA (BELL PEPPERS, SOLANACEAE), Allergy, 53, 1998, pp. 52-54
Citations number
22
Categorie Soggetti
Allergy,Immunology
Journal title
Allergy → ACNP
ISSN journal
01054538
Volume
53
Year of publication
1998
Supplement
46
Pages
52 - 54
Database
ISI
SICI code
0105-4538(1998)53:<52:COAIPS>2.0.ZU;2-S
Abstract
Allergens in spices from the botanic families Apiaceae, Piperaceae, an d Solanaceae were characterized. IgE-immunoblotting and IgE-inhibition experiments revealed broad cross-reactivity among spices and to polle n-derived proteins. Moreover, monoclonal antibodies raised against cro ss-reactive pollen allergens (profilin, Bet v 1) detected homologous p roteins in almost every spice source analyzed. It can be concluded tha t allergy to spices rarely represents an autonomous sensitization, but is rather a consequence of pollen allergy on the basis of immunologic cross-reactivity. (C) Munksgaard 1998.