Y. Kiho et al., DYNAMIC ASPECTS OF PROTEIN FUNCTION I - RATIONALE OF MATHEMATICAL APPROACH, Proceedings of the Japan Academy. Series B Physical and biological sciences, 74(7), 1998, pp. 164-168
Comparison between two amino-acid-sequences was quantified by matrices
. The hydrophilicity of each amino acid was used as a parameter to cha
racterize the sequence and its functional aspect in a water environmen
t. The eigenvalues calculated in the linear transformation give an ima
ge of a biochemical conversion between two amino-acid-sequences.