Pijm. Wuisman et al., CHONDROSARCOMA SECONDARY TO SYNOVIAL CHONDROMATOSIS - REPORT OF 2 CASES AND A REVIEW OF THE LITERATURE, Archives of orthopaedic and trauma surgery, 116(5), 1997, pp. 307-311
Malignant transformation of synovial chondromatosis into chondrosarcom
a is unusual. Thirteen cases and one series have been reported; only f
our of them developed in the hip. The overall survival is about 50%, p
ossibly because of the difficulty of arriving at a correct early diagn
osis (radiographically and histologically) and subsequent adequate sur
gical therapy. We report two patients (ages 30 and 50 years) in whom s
ynovial chondrosarcoma developed in previously excised synovial chondr
omatosis of the hip. The diagnosis was made with modem imaging techniq
ues (computed tomography and magnetic resonance imaging) and verified
by open biopsy. The early recognition allowed a wide limb-saving resec
tion; both patients are disease free 3 and 2 years after surgery.