THORACOSCOPIC T2-T3 SYMPATHICOLYSIS FOR ESSENTIAL HYPERHIDROSIS IN CHILDHOOD - EFFECTS ON PULMONARY-FUNCTION

Thoracoscopic T2-T3 sympathicolysis (TS) is a minimally invasive treat ment for patients suffering from severe, refractory essential hyperhid rosis (EH). TS has previously been shown to be safe and efficacious in children. In order to examine the effects of TS on respiratory functi on, pulmonary function tests (PFT) were performed prior to and 6 weeks and 6 months after TS in 12 children with EH (3 boys; mean age 12.8 /- 2.5 years). Small asymptomatic decreases in forced expiratory volum e in one second (FEV1; -2%), forced expiratory flow after expiration o f 75% of vital capacity (FEF75; -9.6%), total lung capacity (TLC; -1%) , transfer factor for diffusion of carbon monoxide (T-LCO; -7.6%), and transfer coefficient for diffusion of carbon monoxide (K-CO; -1.5%) w ere observed 6 weeks after TS. These changes are comparable to those o bserved in adults but did not reach statistical significance in small children. In line with observations in adults, TLC (and T-L,T-CO) retu rned to baseline values 6 months after TS, whereas FEV1, FEF75, and K- CO remained at their 6-week level. In conclusion, TS causes only small , statistically insignificant, and asymptomatic decreases in pulmonary function in children. TS can, therefore, be considered a safe treatme nt option in children suffering from severe, refractory EH. Pediatr Pu lmonol, 1998; 26:262-264, (C) 1998 Wiley-Liss, Inc.