Kr. Alonso et al., EFFECTS OF IN-VIVO EXPOSURE TO 2,3,7,8-TCDD ON F-1 GENERATION ADULT CHICKENS (GALLUS-GALLUS), Chemosphere (Oxford), 37(9-12), 1998, pp. 1873-1883
White Leghorn chickens (Gallus gallus) were used as surrogate species
for the resident wild turkeys found on the Times Beach, Missouri, Supe
rfund site. Parental chickens were injected with concentrations of 2,3
,7,8-TCDD which modeled soil concentrations before (200 ppb) and after
remediation (1 ppb)[1]. Offspring were followed through development t
o assess alterations in reproductive maturity through the use of a fou
r-way breeding study. F-1 adult females exposed to a maternal dose of
8.6 ng/day began egg production approximately two weeks later than did
F-1 control adult females. By week eight, however, egg production bet
ween groups was equivalent. No differences were observed in eggshell g
land estrogen or progesterone receptor levels. (C) 1998 Elsevier Scien
ce Ltd. All rights reserved.