SOME ASPECTS OF STRUCTURE AND EXPRESSION OF MILK PROTEIN GENES (A REVIEW)

The review considers the specific features of the structural organizat ion of milk protein genes, the functional significance of the 5'-flank ing regions, the binding sites for specific and common nuclear transcr iption factors, the phenomenon of gene insulation that can overcome th e position effects, the tissue-specific expression and skipping of mil k protein gene exons. Special mention is made of the peculiarities of foreign gene expression in connection with the regulatory possibilitie s of 5'-flanking regions.