STUDIES ON SECURIGERA-SECURIDACEA (L.) DEG. ET DORFL. (FABACEAE) SEEDS, AN ANTIDIABETIC EGYPTIAN FOLK MEDICINE

Authors
ALI AA MOHAMED MH KAMEL MS FOUAD MA SPRING O
Citation
Aa. Ali et al., STUDIES ON SECURIGERA-SECURIDACEA (L.) DEG. ET DORFL. (FABACEAE) SEEDS, AN ANTIDIABETIC EGYPTIAN FOLK MEDICINE, Die Pharmazie, 53(10), 1998, pp. 710-715
Citations number
29
Categorie Soggetti
Pharmacology & Pharmacy","Chemistry Medicinal",Chemistry
Journal title
Die Pharmazie → ACNP
ISSN journal
00317144
Volume
53
Issue
10
Year of publication
1998
Pages
710 - 715
Database
ISI
SICI code
0031-7144(1998)53:10<710:SOS(DE>2.0.ZU;2-Y
Abstract
A new cardenolide(-)-14-methoxyhyrcanoside (1) was isolated from the a queous extract of the seeds of Securigera securidacea (L.) Deg. et Dor fl. (Fadaceae) together with five new dihydrobenzofuran derivatives na med securigran I-V (2-6). Kaempferol and astragalin were also islated from the aqueous extract of the flowers. (-)-14- Methoxyhyrcanoside an d the total aqueous extract Of the seeds showed marked chronotropic ac tivity. The total aqueous extract also showed a marked diuretic and se vere hypokalemic effects on the K+-level in serum. The hypoglycemic ef fect of the seeds was also confirmed.