Post-thyroidectomy I-131 whore-body scintigraphy is an important aspec
t in the management of patients with thyroid cancer. The scan is used
to detect residual thyroid tissue and distant functioning metastases.
Extrathyroid I-131 accumulation does not always denote metastatic dise
ase, and several potential sources of false-positive I-131 scans have
been identified. This report presents four cases of benign oral diseas
e as a cause of false-positive I-131 uptake. Benign oral disease has n
ot been documented previously as an important source of false-positive
I-131 whole-body scans.