ENANTIOSELECTIVE NUCLEOPHILIC-SUBSTITUTION OF A 6,6-BICYCLIC DIENYL ACETATE BY PALLADIUM-CHIRAL PHOSPHINE CATALYST

Authors
SHIMIZU I MATSUMOTO Y NISHIKAWA M KAWAHARA T SATAKE A YAMAMOTO A
Citation
I. Shimizu et al., ENANTIOSELECTIVE NUCLEOPHILIC-SUBSTITUTION OF A 6,6-BICYCLIC DIENYL ACETATE BY PALLADIUM-CHIRAL PHOSPHINE CATALYST, Chemistry Letters, (10), 1998, pp. 983-984
Citations number
30
Categorie Soggetti
Chemistry
Journal title
Chemistry Letters → ACNP
ISSN journal
03667022
Issue
10
Year of publication
1998
Pages
983 - 984
Database
ISI
SICI code
0366-7022(1998):10<983:ENOA6D>2.0.ZU;2-E
Abstract
The enantioselective nucleophilic substitution of (+/-)-2 beta-acetoxy -4a beta-methyl-2,3,4,4a, 5,6-hexahydronaphthalene with dimethyl malon ate anion was performed in the presence of palladium-chiral ligand cat alysts to give optically active 2-di(methoxycarbonyl)methyl-4a-methyl- 2,3,4,4a,5, 6-hexahydronaphthalenes.