SYNTHESIS OF BIOLOGICALLY-ACTIVE COMPOUNDS BASED ON 2-FERROCENYLMETHYLENE-3-QUINUCLIDONE

Authors
KLIMOVA EI RAMIREZ LR GARCIA MM ESPINOSA RG MELESHONKOVA NN
Citation
Ei. Klimova et al., SYNTHESIS OF BIOLOGICALLY-ACTIVE COMPOUNDS BASED ON 2-FERROCENYLMETHYLENE-3-QUINUCLIDONE, Russian chemical bulletin, 45(11), 1996, pp. 2602-2609
Citations number
16
Categorie Soggetti
Chemistry
Journal title
Russian chemical bulletin → ACNP
ISSN journal
10665285
Volume
45
Issue
11
Year of publication
1996
Pages
2602 - 2609
Database
ISI
SICI code
1066-5285(1996)45:11<2602:SOBCBO>2.0.ZU;2-5
Abstract
Biologically active nitrogen heterocycles (1-7) containing ferrocene a nd quinuclidine fragments were synthesized. 3-Methylene-2-ferrocenylme thylenequinuclidine forms adducts with N-phenylimides of azodicarboxyl ic (the structure was established by X-ray structural analysis) and ma leic acids. 3-Methylene-2-ferrocenylmethylenequinuclidine also undergo es [4+2]-cyclodimerization when heated and adds salts of the ferroceny lmethylene-1-azoniabicyclo[2.2.2]oct-3-yl cation at the terminal methy lene group to form a linear addition product.