DNA measurements and histopathological evaluation were performed in 17
patients treated with adjuvant tamoxifen in early breast cancer and w
ho developed endometrial carcinoma during or after tamoxifen therapy.
The tumours were exclusively characterised by low grade malignancy and
euploid DNA pattern except for two cases. The hazards of giving long-
term tamoxifen thus seem to be low. (C) 1998 Elsevier Science Ltd. All
rights reserved.