Genital HSV-2 infections have increased in prevalence by more than 30%
over the last two decades with 1 in 5 adults now positive for antibod
ies to HSV-2. Fifteen percent of white men, 20% of white women, 35% of
black men, and 55% of black women are HSV-2 seropositive. Prevalence
of HSV-2 has in creased 5-fold among teenagers and has doubled among t
hose in their twenties.(10) Since HSV-1 causes from 20% to 40% of firs
t episodes of genital herpes, these figures underestimate the total bu
rden of genital herpes in this country.