LOWERED ANTIOXIDANT STATUS OF RED-BLOOD-CELLS IN POSTPARTURIENT HEMOGLOBINURIA OF BUFFALOS

Citation
Sk. Chugh et al., LOWERED ANTIOXIDANT STATUS OF RED-BLOOD-CELLS IN POSTPARTURIENT HEMOGLOBINURIA OF BUFFALOS, Veterinary research communications, 22(6), 1998, pp. 385-388
Citations number
12
Categorie Soggetti
Veterinary Sciences
ISSN journal
01657380
Volume
22
Issue
6
Year of publication
1998
Pages
385 - 388
Database
ISI
SICI code
0165-7380(1998)22:6<385:LASORI>2.0.ZU;2-O
Abstract
The antioxidant status of the red blood cells of buffaloes (n = 20) su ffering from post-parturient haemoglobinuria (PPH) was assessed by com paring their tocopherol (vitamin E) and reduced glutathione contents w ith those of red blood cells from apparently healthy buffaloes (n = 20 ). The red cell tocopherol content of the diseased buffaloes (1.76 +/- 0.11 mu g/ml) was significantly (p < 0.01) lower than that of healthy buffaloes (2.45 +/- 0.14 mu g/ml). This may be the first report compa ring the concentration of tocopherol in the red blood cells of buffalo es suffering from PPH and apparently healthy buffaloes. There was a dr astic reduction in the reduced glutathione content in the red cells of haemoglobinuric buffaloes (23.74 +/- 2.86 mg%) compared to the health y control buffaloes (73.71 +/- 3.87 mg%). The diseased buffaloes also exhibited severe hypophosphataemia. These findings suggest that an imp aired or insufficient antioxidant potential of the red blood cells in this disease in buffaloes is associated with the phosphorus deficiency .