Objective: To present a clinical case of an elderly person with psycho
sis and to discuss associated diagnostic and treatment issues. Methods
: A case from I of the authors' clinical practices was presented in En
glish and French to several groups of Canadian psychiatrists attending
a teaching day on psychosis. Three geriatric psychiatrists acted as f
acilitators, soliciting the clinical experiences of the participants i
n the discussion The authors integrated clinical content fr om these s
essions with results of a Medline search on psychosis in elderly perso
ns. Results: The assessment of elderly patients with psychosis is more
often than in younger patients by overlying organicity, including del
irium due to illness or medication use dementia, or sensory deficits.
Treatment might further worsen cognitive, affective and functional imp
airment through adverse effects such as extrapyramidal symptoms (leadi
ng to decreased mobility and general functioning;), anticholinergic ef
fects (predisposing to delirium), and hypotension (predisposing to fal
ls). Newer antipsychotics with less hazardous side effect profiles hav
e an increasing role, but they must be coupled with psychosocial suppo
rt to maximize the patient's independent functioning and quality of li
fe after discharge. Conclusions: Assessment and treatment of the elder
ly person with psychosis must consider a wide variety of biopsychosoci
al variables seeking to minimize further treatment-related deteriorati
on. Controlled studies of antipsychotics in elderly people must be con
ducted in a variety of diagnostic situations that reflect their actual
use in the community and information must be propagated effectively a
mong general psychiatrists, family physicians, and geriatric psychiatr
ists. The role of nonpharmacologic interventions in elderly persons wi
th psychosis is even less well understood and deserves further study.