M. Fingerman et al., HORMONALLY-REGULATED FUNCTIONS IN CRUSTACEANS AS BIOMARKERS OF ENVIRONMENTAL-POLLUTION, Comparative biochemistry and physiology. C. Comparative pharmacologyand toxicology, 120(3), 1998, pp. 343-350
The effects of organic and inorganic contaminants on functions regulat
ed by hormones in crustaceans are being investigated with increasing f
requency because several of these phenomena show promise of being usef
ul biomarkers of environmental contamination. Heavy metals and organic
compounds have been found in studies with crustaceans to negatively a
ffect hormonally-regulated functions, specifically reproduction, molti
ng, blood glucose level, and pigmentary effecters. Neurotransmitters,
including 5-hydroxytryptamine and dopamine, have been identified as be
ing involved in stimulating or inhibiting release of specific crustace
an neurohormones such as the pigment-dispersing and pigment-concentrat
ing ones involved in color changes. The effects of pollutants on at le
ast some of these hormonally-regulated processes appear due at least i
n part to impacting release of a neurohormone, possibly by affecting r
elease of the neurotransmitter that normally stimulates release of tha
t particular neurohormone. (C) 1998 Elsevier Science Inc. All rights r
eserved.