The effects of amines found in sausages (cadaverine, histamine, 2-phen
ylethylamine, putrescine, spermidine, spermine, tryptamine and tyramin
e) on the activity of four aminopeptidases (AP 1,AP 2, AP 3 and AP 4)
from Lactobacillus sake were determined, Histamine caused the stronges
t inhibition on AP 1 followed by tryptamine, The activity of AP 2 was
markedly reduced by tryptamine and 2-phenylethylamine. AP 3 was inhibi
ted at similar levels by histamine, tyramine and tryptamine but activa
ted by putrescine, cadaverine and spermidine, Agmatine caused the stro
ngest inhibition on AP 4.