Background Ultrasound biometry for axial length measurement may be per
formed either by directly putting the probe on the: cornea or by using
a water immersion technique. Our goal was to examine whether there ar
e unsystematic differences between both techniques present besides sys
tematic differences that can be compensated by adjusting calculation f
ormula constants. Patients, materials and methods We examined 288 pati
ents in a prospective, randomized trial. There was no ocular pathology
present beside cataract. Axial lengths <21 mm and >27 mm were exclude
d. We calculated which IOL power would have given the desired refracti
ve result by using the postoperative refraction and data of the lens i
mplanted. Results A systematic difference between both techniques is p
resent. With the contact technique, axial length is measured 0,15 mm s
horter. This requires adjustment of formula constants. Furthermore, th
ere is an unsystematic difference that leads to 18% greater calculatio
n errors (difference between IOL calculated preoperatively and ideal I
OL) with the contact technique. Mean absolute error was 0.43 +/- 0.38
dpt for the immersion group and 0.53 +/- 0.48 dpt for the contact grou
p. Conclusions To minimize postoperative refractive errors, ultrasound
biometry using immersion technique should be preferred.