IS ESTROGEN NECESSARY AFTER HYSTEROSCOPIC INCISION OF THE UTERINE SEPTUM

Study Objective. To evaluate the influence of estrogen alter hysterosc opic incision oi the uterine septum. Design. Prospective, randomized, blinded study. Setting. A national referral university hospital. Patie nts. Fifty women in whom hysterosalpingography (HSG) showed a fundal d efect and had septate uterus confirmed by laparoscopy. Interventions, Preoperative HSG, hysteroscopic incision of the septum, and postoperat ive HSG. Four patients were omitted from the analysis because the angl e of the uterus could not be corrected, as shown by postoperative HSG. Group 1 (23 women) received conjugated estrogen and progesterone post operatively and group 2 (23 women) received no hormone. Measurements a nd Main Results. The ratios of the length of the septum to the length of the uterus in the HSGs obtained preoperatively (a/b) and postoperat ively (a'/b') were calculated and subtracted from each other (a/b-a'/b '). The means of the subtractions in the two groups were compared. The t test was used for statistical comparison. The results showed no sta tistically significant difference. Conclusion. Estrogen has no apparen t role alter hysteroscopic incision of the septum.