Ciguatera fish poisoning is the most common form of toxin-related food
poisoning in the United States. Originating from dinoflagellates livi
ng on coral reefs, it is spread up the food chain and affects humans w
ho ingest the ciguatoxic fish. Ciguatera is primarily endemic in tropi
cal regions of the world. It is a self-limiting disease that presents
with characteristic gastrointestinal, neurological, and cardiovascular
symptoms, Recent advances in testing procedures and symptom recogniti
on has improved ciguatoxin identification and clinical management. How
ever, there is still a need for better diagnostic, preventive, and rep
orting protocols to more accurately study and understand this diverse
and temporarily debilitating clinical syndrome.