ANTERIOR-PITUITARY DEVELOPMENT AND PIT-1 GHF-1 TRANSCRIPTION FACTOR/

Authors
DELAHOYA M VILA V JIMENEZ O CASTRILLO JL
Citation
M. Delahoya et al., ANTERIOR-PITUITARY DEVELOPMENT AND PIT-1 GHF-1 TRANSCRIPTION FACTOR/, Cellular and molecular life sciences, 54(10), 1998, pp. 1059-1066
Citations number
38
Categorie Soggetti
Biology,"Cell Biology",Biology
Journal title
Cellular and molecular life sciences → ACNP
ISSN journal
1420682X
Volume
54
Issue
10
Year of publication
1998
Pages
1059 - 1066
Database
ISI
SICI code
1420-682X(1998)54:10<1059:ADAPGT>2.0.ZU;2-8
Abstract
Anterior pituitary differentiation is a well-established paradigm in m ammalian organogenesis. PIT1/GHF1, a homoeotic gene, plays a key role in terminal pituitary differentiation. Recently, a;new set of transcri ption factors involved in early pituitary differentiation have been id entified: Lhx-3, Lhx-4, P-OTX and Prop1. A pituitary-specific transcri ptional cascade regulating a developmental programme leads to, the det ermination of the mature cell types.