During a 5-year period, superior mesenteric vein (SMV) thrombosis was
detected with computed tomography (CT) in six patients shortly after a
n appendectomy. No sign of SMV was present at appendectomy, and a peri
od of more than 2 weeks free of clinical symptoms had elapsed between
the appendectomy and the onset of the SMV thrombosis. In four cases, t
he appendicitis was complicated. These patients had nonspecific: signs
and symptoms, although two of them; had elevation of blood hepatic en
zyme levels. In all cases, postcontrast CT demonstrated enlargement of
the SMV, with well-defined enhancement of the vascular wall and an in
traluminal clot. In one case, CT showed extension of the thrombus to:t
he portal vein with the presence of low-attenuation areas in the liver
, consistent with hepatic infarcts. Two patients had predisposing dise
ases: idiopathic hypersplenism in one case and chronic hepatic disease
in the other. SMV thrombosis is a possible complication of appendicit
is, and early appendectomy in appendicitis can prevent this complicati
on. Moreover, as in any abdominal surgery, early appendectomy may be c
omplicated by thrombosis of the SMV, thus creating problems of postope
rative diagnosis. The complication is more frequent when the initial o
peration is performed under difficult conditions (peritonitis), or whe
n the patient presents with a coagulopathy. CT is useful in the diagno
sis of SMV thrombosis, thus leading to early management with anticoagu
lant therapy, with a view to avoiding complications such as intestinal
ischemia, portal vein thrombosis, and hepatic infarction.