Background: To identify and differentiate agenesis and severe atrophy
of the right hepatic lobe on computed tomography (CT). Methods: The CT
examinations of three cases of agenesis and 11 cases of severe atroph
y of the right hepatic lobe were reviewed. We evaluated visibility of
the three hepatic veins, the two main portal veins (including their br
anches if necessary), the dilated intrahepatic ducts, enlargement of t
he medial and lateral segments of the left lobe and caudate lobe of th
e liver, presence of a retrohepatic gallbladder, hyperattenuation of t
he atrophic liver parenchyma, posterolateral interposition of the hepa
tic flexure of the colon, and upward migration of the right kidney. Re
sults: In the three cases of agenesis, no structure can be recognized
as the right hepatic vein, right portal vein, or dilated right intrahe
patic ducts. In the 11 cases of severe lobar atrophy, the right portal
vein (or its branches) was recognized in eight cases, the right hepat
ic vein in four cases, and the dilated right intrahepatic ducts in 11
cases. The degree of enlargement of the lateral segment does not neces
sarily change inversely with the size of the medial segment and the ca
udate lobe. The retrohepatic gallbladder is present in eight cases (tw
o in agenesis and six in atrophy). The phenomenon of hyperattenuation
of the atrophic liver parenchyma was noted in six cases. Conclusion: E
ven though a retrohepatic gallbladder and a severely distorted hepatic
morphology due to compensatory hypertrophy of the left and caudate lo
bes may raise a suspicion of agenesis of the right lobe of the liver,
absence of visualization of all of the right hepatic vein, right porta
l vein and its branches, and dilated right intrahepatic ducts is a pre
requisite of the diagnosis of agenesis of the right hepatic lobe on CT
. In severe lobar atrophy, at least one of these structures is recogni
zable.