FOR DISCUSSION - LIVE ATTENUATED VACCINES FOR GROUP-B MENINGOCOCCUS

Authors
TANG C MOXON R LEVINE MM
Citation
C. Tang et al., FOR DISCUSSION - LIVE ATTENUATED VACCINES FOR GROUP-B MENINGOCOCCUS, Vaccine, 17(2), 1999, pp. 114-117
Citations number
30
Categorie Soggetti
Veterinary Sciences",Immunology,"Medicine, Research & Experimental
Journal title
Vaccine → ACNP
ISSN journal
0264410X
Volume
17
Issue
2
Year of publication
1999
Pages
114 - 117
Database
ISI
SICI code
0264-410X(1999)17:2<114:FD-LAV>2.0.ZU;2-P
Abstract
Current attempts at preventing infections caused by group B Neisseria meningitidis are largely directed on generating immune responses to ou ter membrane proteins or the lipopolysaccharide of this organism. We s uggest an alternative approach: the use of a live, attenuated strain o f Neisseria meningitidis which could be delivered mucosally to elicit both local and systemic immune responses. (C) 1998 Elsevier Science Lt d. All rights reserved.