Recent seroprevalence studies have shown alarming rates of HIV infecti
on among severely mentally ill men and women in large urban areas, and
HIV behavioral epidemiology research indicates that a substantial pro
portion of seriously mentally ill adults engage in activities that inc
rease their vulnerability to HIV/AIDS. In this paper the research lite
rature on HIV prevention interventions is reviewed including reports t
hat have described HIV prevention programs, studies that have used unc
ontrolled pre- and postintervention methods to evaluate risk reduction
interventions, and those that have used rigorous randomized designs a
nd examined risk behavior change. Collectively, these studies show tha
t intensive, small-group interventions that target a variety of risk-r
elated dimensions - including knowledge, attitudes, and motivations, a
nd behavioral and cognitive skills - can produce at least short-term r
eductions in high-risk sexual behavior among the severely mentally ill
. A number of gaps in the research literature are identified including
the need to: (a) better tailor interventions to risk situations encou
ntered by the mentally ill; (b) develop gender-tailored interventions;
(c) examine and implement HIV prevention programs so they help person
s sustain behavior change; (d) explore one-on-one counseling and commu
nity-level intervention methods; and (e) develop risk reduction interv
entions for already-seropositive individuals. implications for service
provision are discussed. (C) 1997 Elsevier Science Ltd.