Medical and neuropsychiatric sequelae of HIV infection present a spect
rum of diagnostic and treatment challenges to mental health clinicians
. Both HIV and the many opportunistic infections that manifest in pati
ents due to their immunocompromised state also can affect the central
nervous system (CNS). Thus, mental health clinicians need to be famili
ar with the diagnosis and management of HIV-related medical and psychi
atric complications. This article provides an overview of the CNS-rela
ted manifestations resembling from HIV disease, including HIV-related
dementia, psychotic disorders, delirium CNS opportunistic infections a
nd tumors, systemic abnormalities, psychoactive substances, and the ad
verse effects of certain medical treatments. Treatment strategies for
individuals with HIV disease and comorbid severe mental illness are ou
tlined and recommendations for future research are offered. (C) 1997 E
lsevier Science Ltd.