We describe a case of a 43-yr-old woman presenting a progressive pleur
al effusion. The patient was known to have an acute myeloid leukemia i
n complete reemission after allogenic bone marrow transplantation. Sus
picion of pleural carcinosis was raised cytologically and confirmed by
immunocytochemistry. DNA-cytometry, and atomic force microscopy. We e
mphasize the use of these additional methods for the distinction of ad
enocarcinoma cells in effusions from reactive mesothelial cells. (C) 1
998 Wiley-Liss, Inc.