Background: Psychogenic excoriation, characterized by excessive scratc
hing or picking of the skin, is not yet recognized as a symptom of a d
istinct DSM-IV disorder. The purpose of this study was to provide data
regarding the demographics, phenomenology, course of illness, associa
ted psychiatric comorbidity, and family history of subjects with psych
ogenic excoriation. Method: Thirty-four consecutive subjects were recr
uited from an outpatient dermatology practice and by advertisement. Su
bjects completed the Structured Clinical Interview for DSM-IV augmente
d with impulse control disorder modules, the Yale-Brown Obsessive Comp
ulsive Scale, and a semistructured interview for family history, demog
raphic data, and clinical features. Results: Most subjects were women
who described a mean age at onset of 38 years and a chronic course. Su
bjects excoriated multiple sites, most frequently the face. The behavi
or caused substantial distress and dysfunction. All 34 subjects met cr
iteria for at least 1 comorbid psychiatric disorder, with a mood disor
der the most common. Family histories were notable for depressive diso
rders and psychoactive substance use disorders. Most subjects experien
ced both mounting tension before excoriation and relief after excoriat
ion as in impulse control disorders. A minority of subjects excoriated
skin as part of obsessive-compulsive disorder. Body dysmorphic disord
er with preoccupation about the skin's appearance precipitated excoria
tion in about a third of subjects. Conclusion: Psychogenic excoriation
is chronic, involves multiple sites, and is associated with a high ra
te of psychiatric comorbidity. The behavior associated with the excori
ation is heterogeneous and spans a compulsive-impulsive spectrum. Most
subjects in this sample described features of an impulse control diso
rder.