Kh. Sun et al., ENE REACTION WITH PUMMERER-TYPE REACTION INTERMEDIATE OF 1-[(2-METHYLTHIO)ETHANOYL]PYRROLIDINE - A NOVEL SYNTHESIS OF TRICHONINE, Journal of the Chinese Chemical Society (Taipei), 45(5), 1998, pp. 625-627
Pummerer-type reaction intermediate 2 of 1-[(2-methylthio)ethanoyl]pyr
rolidine (1) has been found to react with 1-alkenes to afford ene addu
cts 3. Trichonine 4 was synthesized from the adduct 3g.