Quality-of-life (QOL) measures have become valuable additions to tradi
tional morbidity and mortality outcomes in evaluating the progression
of disease or the efficacy of medical interventions. With significant
increases in longevity and an expanding treatment repertoire, QOL issu
es for people with HIV/AIDS have become increasingly important. Furthe
rmore, as people are living longer with HIV/AIDS and the population in
general ages, the number of persons older than age 50 who have HIV/AI
DS is increasing. As QOL issues become more important for people with
HIV/AIDS and as the population with HIV/AIDS ages, several issues rela
ted to QOL among older people arise. These include conceptual issues r
elated to QOL and aging, as well as methodological issues of QOL asses
sments among older persons. This article begins with a brief discussio
n of why QOL is important to measure, various measurement strategies,
and QOL comparisons between HIV/AIDS populations and other chronic dis
ease groups. This is followed by a discussion of conceptual and method
ological issues in measuring QOL among older persons. Finally, the aut
hors conclude with recommendations for future research.