ANALYSIS OF ACIDIC COMPOUNDS USING CAPILLARY ELECTROCHROMATOGRAPHY

Capillary electrochromatography, CEC, is a hybrid of CE and HPLC and i s rapidly gaining interest as a potential complementary technique. Thi s paper provides an overview of literature concerning the separation o f acidic compounds by CEC which fall into three distinct groups. These groups are those performed using capillaries packed with novel or uni que stationary phases designed for CEC, and a smaller group where stan dard HPLC stationary phases packings such as ODS has been used. The th ird group involves the use of surface coated capillaries. This paper r eviews the separation of acidic compounds by CEC and also includes a n umber of novel applications to illustrate the separation approaches an d the analytical performance possible. (C) 1998 Elsevier Science B.V. All rights reserved.