Objective: To compare the characteristics of patients who did and did
not respond to a request for information regarding their cryopreserved
pre-embryos. Design: Mail survey. Setting: Academic-assisted reproduc
tive technology program. Patient(s): One hundred thirty-six patients w
ith cryopreserved pre-embryos. Intervention(s): Patients were surveyed
by first-class mail regarding their plans for their cryopreserved pre
-embryos and their interest in embryo donation.Main Outcome Measure(s)
: Age, number of stored pre-embryos, and duration of storage of respon
ders and nonresponders at 6 weeks after mailing. Result(s): Eighty-thr
ee patients (62%) did not respond to the survey. Compared with respond
ers, nonresponders were significantly older at the time of embryo cryo
preservation, had fewer pre-embryos cryopreserved, and had the pre-emb
ryos cryopreserved for a longer duration. Five responders (9%) express
ed an interest in embryo donation. Three patients requested disposal o
f pre-embryos. Sixteen surveys (12%) were returned as undeliverable. A
s a group, these patients had the fewest pre-embryos cryopreserved and
had the longest duration of storage. Conclusion(s): A disturbing numb
er of patients with cryopreserved pre-embryos ignored efforts by our p
rogram to maintain contact. Older patients with few cryopreserved pre-
embryos may require special attention to avoid abandonment. (Fertil St
eril(R) 1998;70:949-51. (C) 1998 by American Society for Reproductive
Medicine.).