PIPERONAL AS ELECTROPHILE IN THE BAYLIS-HILLMAN REACTION - A SYNTHESIS OF HYDROXY-BETA-PIPERONYL-GAMMA-BUTYROLACTONE DERIVATIVE

Authors
ALMEIDA WP COELHO F
Citation
Wp. Almeida et F. Coelho, PIPERONAL AS ELECTROPHILE IN THE BAYLIS-HILLMAN REACTION - A SYNTHESIS OF HYDROXY-BETA-PIPERONYL-GAMMA-BUTYROLACTONE DERIVATIVE, Tetrahedron letters, 39(47), 1998, pp. 8609-8612
Citations number
12
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
39
Issue
47
Year of publication
1998
Pages
8609 - 8612
Database
ISI
SICI code
0040-4039(1998)39:47<8609:PAEITB>2.0.ZU;2-Y
Abstract
Aromatic aldehydes are reluctant to serve as substrates for the Baylis -Hillman reaction at all under the relatively mild conditions. In our research, we have achieved that piperonal could be an useful substrate in this reaction, employing ultrasound technique. The adduct obtained was used in the preparation of key intermediates for the total synthe sis of hydroxylated lignans. (C) 1998 Elsevier Science Ltd. All rights reserved.