This study aimed to investigate the association between daily air poll
ution levels and the occurrence of acute respiratory signs and symptom
s among people with asthma or asthma-like problems. Thirty eight subje
cts in the southern Swedish city of Landskrona kept a daily diary for
10 weeks. The daily prevalence of symptoms, supplementary bronchodilat
or use and peak how deviations were compared with measurements of envi
ronmental nitrogen dioxide (NO2), sulphur dioxide, temperature and hum
idity in the city. The occurrence of severe asthma, both during the da
y and during the evening, was significantly positively associated with
the concurrent 24 h average concentration of NO2, which never exceede
d 72 mu g.m(-3). A correlation of borderline significance was found be
tween the use of on-demand medication and the NO2 level. However, peak
flow deviations were not associated with air pollution or weather con
ditions, which may be explained by the beneficial effect of bronchodil
ators used by 28 of the subjects, The results of this study confirm th
ose of some earlier studies and suggest that aggravation of asthma is
related to daily variations in air quality, as indicated by relatively
low ambient concentrations of nitrogen dioxide. These results also in
dicate that it may be appropriate to examine severe asthma symptoms se
parately.