This prospective clinical pilot study describes the clinical utility a
nd cost effectiveness of computed tomography (CT) with contrast in the
diagnosis and management of pulmonary embolism. The setting is a univ
ersity teaching hospital, and the 20 patients, 26 to 81 years old, wer
e found to have CT findings consistent with pulmonary embolism, Intral
uminal pulmonary artery clots were observed on CT and contributed to c
linical management, often obviating pulmonary arteriography. CT, parti
cularly spiral CT, may demonstrate pulmonary embolism and offers advan
tages over ventilation-perfusion lung scanning and pulmonary arteriogr
aphy in making the diagnosis of pulmonary embolism in high-risk patien
ts or patients with preexisting parenchymal lung disease, (C) Elsevier
Science Inc., 1997.