B. Pchelka et al., LIPASE-CATALYZED KINETIC RESOLUTION OF THE RACEMIC MIXTURES OF 1-ARYLOXY-3-NITRATO-2-PROPANOLS AND 1-ARYLOXY-3-AZIDO-2-PROPANOLS, Synthetic communications, 28(23), 1998, pp. 4355-4364
The racemic mixtures of 1-aryloxy-3-nitrato-2-propanols and 1-aryloxy-
3-azido-2-propanols were resolved with moderate selectivity by the lip
ase-mediated acylation with vinyl acetate. The effects of the nature,
position, and spatial requirements of the phenyl-ring substituents on
the resolution degree were investigated.