ENANTIOSELECTIVE HYDROGENATION OF FUNCTIONALIZED KETONES - SYNTHESIS AND APPLICATION OF NEW CHIRAL AMINOPHOSPHINE-PHOSPHINITE LIGANDS

Authors
PASQUIER C EILERS J REINERS I MARTENS J MORTREUX A AGBOSSOU F
Citation
C. Pasquier et al., ENANTIOSELECTIVE HYDROGENATION OF FUNCTIONALIZED KETONES - SYNTHESIS AND APPLICATION OF NEW CHIRAL AMINOPHOSPHINE-PHOSPHINITE LIGANDS, Synlett, (10), 1998, pp. 1162
Citations number
32
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synlett → ACNP
ISSN journal
09365214
Issue
10
Year of publication
1998
Database
ISI
SICI code
0936-5214(1998):10<1162:EHOFK->2.0.ZU;2-D
Abstract
The chiral new aminophosphine-phosphinites (AMPP's 1-7) have been synt hesised and applied successfully in the enantioselective hydrogenation of dihydro-4,4-dimethyl-2,3-furandione 8, N-benzylbenzoylformamide 9, and ethylpyruvate 10 providing the hydroxy products in up to 97, 95, and 80% ee, respectively.