Zl. Gong et Zj. Zhang, CYCLODEXTRIN-BASED OPTOSENSOR FOR THE DETERMINATION OF QUININE, Fresenius' journal of analytical chemistry, 357(8), 1997, pp. 1093-1096
A flow-through optosensor for quinine is described. It has been develo
ped in conjunction with a flow-injection analysis system and uses immo
bilized beta-cyclodextrin as the sensing agent. The detection limit fo
r quinine was 0.20 ng ml(-1) with a relative standard deviation of 2.1
% for the determination of 0.05 mu g ml(-1) (n = 7) of quinine. The me
thod has been successfully tested for the determination of quinine in
some pharmaceutical preparations.